Sunday | PM | 7:00 | 7:30 | 8:00 | 8:30 | 9:00 | 9:30 | 10:00 | 10:30 |
| ABC | The Disney Sunday Movie | Spenser: For Hire | Dolly | Buck James |
| CBS | 60 Minutes | Murder, She Wrote | CBS Sunday Night Movie |
| FOX | 21 Jump Street | Werewolf | Married... with Children | The Tracey Ullman Show | Duet | Local |
| NBC | Our House | Family Ties | My Two Dads | NBC Sunday Night at the Movies |
Monday
| PM | 8:00 | 8:30 | 9:00 | 9:30 | 10:00 | 10:30 |
| ABC | MacGyver | Monday Night Football |
| CBS | Frank's Place | Kate & Allie | Newhart | Designing Women | Cagney & Lacey |
| NBC | ALF | Valerie's Family | NBC Monday Night at the Movies |
Tuesday
| PM | 8:00 | 8:30 | 9:00 | 9:30 | 10:00 | 10:30 |
| ABC | Who's the Boss? | Growing Pains | Moonlighting | thirtysomething |
| CBS | Houston Knights | Jake and the Fatman | The Law and Harry McGraw |
| NBC | Matlock | J.J. Starbuck | Crime Story |
Note: ABC premiered The Wonder Years afterSuper Bowl XXII and then aired the rest of its season on Tuesdays 8:30pm. NBC aired In the Heat of the Night Tuesdays 9:00pm starting March 1988.
Wednesday Thursday Note: The Days and Nights of Molly Dodd was an NBC spring replacement in the 9:30 p.m. time slot.
Friday Saturday | PM | 8:00 | 8:30 | 9:00 | 9:30 | 10:00 | 10:30 |
| ABC | Once a Hero | Ohara | Spenser: For Hire |
| CBS | My Sister Sam | Everything's Relative | Leg Work | West 57th |
| FOX | Mr. President | The New Adventures of Beans Baxter | Second Chance | Women in Prison | Local |
| NBC | The Facts of Life | 227 | The Golden Girls | Amen | Hunter |
