Baccarin joins Claire Danes, Mandy Patinkin and Damian Lewis in the political thriller, which tells the story of Scott Brody (Lewis), an American POW who is rescued from the Middle East.
Meanwhile, a suspicious CIA operative (Danes) thinks he may have been turned into a terrorist and released intentionally.
According to Deadline.com Baccarin will take on the role of Jessica Brody, Scott's smart, strong wife. She replaces British actress Laura Fraser, who played the role in the pilot.
Baccarin played the reptilian alien queen, Anna, in ABC's recent "reimagining" of '80s sci-fi hit 'V.' Although it debuted to a warm critical reception, the series never really caught fire with viewers, and it's ratings maintained a downward trajectory. On May 13 ABC announced that it was cancelling 'V' after two seasons.
'Homeland,' which comes from '24' executive producer Howard Gordon and is based on the Israeli TV series 'Prisoners of War,' became one of the most eagerly anticipated new dramas this pilot season. The hour-long drama is due to launch on Showtime this fall.