In the first promo for the new season of The Big Bang Theory, things are getting turned upside down, literally and figuratively.

First off, Howard (Simon Helberg) is floating every which way in outer space after tying the knot last May and subsequently blasting off into the stars. Back on planet Earth, Sheldon (Jim Parsons) and Amy (Mayim Bialik) seem to be on shaky ground. But will he be able to win her back?

Kevin Sussman promoted to a series regular on The Big Bang Theory

Watch the clip and find out:

The new season of The Big Bang Theory premieres on Thursday, Sept. 27 at 8/7c on CBS.