According to Deadline, the 'Saturday Night Live' veteran will guest host the daytime talk show all throughout September.
Shannon will make her first appearance on Tue., Sept. 6 alongside Sara Gilbert, Julie Chen, Sharon Osbourne and Sheryl Underwood.
Leah Remini and Holly Robinson Peete will not return, while original co-host Marissa Jaret Winokur departed during the show's first season.
In addition to Shannon, Kris Jenner will also act as a guest host, filling in for Osbourne from time to time.
Shannon has also booked a recurring role on ABC's 'The Middle.' She'll play Janet, sister to Patricia Heaton's main character, Frankie.
Tell us: Are you excited to see Molly Shannon on 'The Talk'?