By Tim Kenneally

LOS ANGELES (TheWrap.com) - "Enlightened" is no more.

HBO has canceled the drama-comedy, which starred Laura Dern, after two seasons.

"It was a very difficult decision," the network said. "We've decided not to continue 'Enlightened' for a third season. We're proud of the show and we look forward to working with Mike White and Laura Dern in the future."

The second, eight-episode season of "Enlightened" wrapped in early March.

Created by "The School of Rock" writer Mike White, "Enlightened" starred Dern as Amy Jellicoe, who decides to become an agent of change after suffering a mental breakdown.

Luke Wilson and Diane Ladd also starred.

Though the series had its fans, "Enlightened" failed to capture much of an audience. With its Season Two premiere in January, the series drew just 300,000 viewers, which though small, was a 43 percent boost over the series premiere.